Antibacterial and antifungal activity of curcumin and methylene blue associated with laser on bacterial and fungal strains

Objective:To analyze the effect of methylene blue and 10% curcumin in fungi and bacteria through an in vitrostudy using photodynamic therapy (PDT). Methods:Curcumin and methylene blue were photosensitized by a Photon Lase III laser applied for 90 s in a dark environment within a laminar flow chamber. Enterococcus faecalisand Candida albicans strains were cultured and standardized.Then, a minimum inhibitoryconcentration (MIC) assay was conducted for these photosensitizers, with concentration variations and incubation to evaluate their antimicrobial activity. Results:With PDT, Curcumin had significant antibacterial activity against E. faecalis (MIC = 250 µg/mL).In contrast, methylene blue had antibacterial activity against E. faecalis (MIC < 12.5 µg/mL with PDT) and antifungal activity against C. albicans (MIC <12.5 µg/mL with or without PDT).Both agents showed greater efficacy in the presence of the laser.The results suggest that curcumin and methylene blue associated with laser may effectively treat microbial infections. Conclusion:Further research is needed to evaluate the efficacy and safety of using these agents in animal and human models and theireffectiveness against different bacterial and fungal strains.

Aspectos radiológicos do baço intrapancreático / Radiological aspects of intra-pancreatic spleen

Baço ­ acessório localizado dentro do parênquima pancreático ­ é uma anomalia congênita do tecido esplênico, com características morfológicas e histológicas semelhantes ao baço normal apresentado, geralmente, na cauda do pâncreas. O baço acessório intrapancreático (BAI) trata-se, sobretudo, de uma lesão benigna, usualmente assintomática e encontrada incidentalmente em estudos de imagem, mas que suscitam frequentemente uma preocupação de malignidade e podem ser radiologicamente indistinguíveis de tumores neuroendócrinos, tumores pancreáticos e adenocarcinomas. O presente estudo visa, portanto, relatar um caso de baço acessório intrapancreático através da tomografia computadorizada (TC) e ressonância magnética (RM), além de correlacionar os achados radiográficos do relato de caso com outros métodos radiológicos encontrados na revisão de literatura. As informações contidas foram obtidas por meio de revisão do prontuário, entrevista com o paciente, registro fotográfico dos métodos diagnósticos em geral e dados laboratoriais, aos quais o paciente foi submetido. Nesse contexto, o relato de caso é de um homem com história prévia de carcinoma de células renais que, após realização de nefrectomia total à esquerda e de linfonodos retroperitoneais, constatou no seguimento de seus exames de controle pós-operatório uma imagem nodular na cauda pancreática sugestiva de metástase, mas que, através do estudo tomográfico e de RM, foi possível realizar o correto diagnóstico, tratando-se apenas de uma afecção benigna assintomática e de intervenção conservadora descrita como BAI (AU).

The spleen, an accessory organ located within the pancreatic parenchyma, is a congenital anomaly of the splenic tissue with morphological and histological characteristics resembling a normal spleen, usually in the tail of the pancreas. The intra-pancreatic accessory spleen (IPAS) is mainly a benign lesion, being usually asymptomatic and found on imaging studies on an incidental basis, but which often raises concern about malignancy and may be radiographically indistinguishable from neuroendocrine tumors, pancreatic tumors, and adenocarcinomas. Therefore, the present study aims to report a case of IPAS using computed tomography (CT) and magnetic resonance (MR) imaging, in addition to correlating the radiographic findings of the case report with other radiological methods in the literature review. Information was obtained by reviewing medical records, conducting interviews with the patient, and using diagnostic photographs and laboratory data. In this context, the case report is of a male patient with previous history of renal cell carcinoma who had undergone total left nephrectomy and resection of retroperitoneal lymph nodes. Post-operative followed-up exams showed a nodular image in the pancreatic tail suggestive of metastasis, but whose correct diagnosis was possible by CT and MR studies as only an asymptomatic benign affection was shown, meaning that only a conservative intervention was necessary (AU).

Sleeping and dreaming in Greek mythology.

This article aims to emphasize the major influence of Ancient Greek Mythology on modern sleep medicine. An analysis of Greek texts and medical literature using the MeSH terms Greek mythology, sleep, Greek Gods, and myths was conducted to identify mythological references related to sleep medicine. The findings are discussed concerning etymology, the early conceptualization of some disorders, and the developing characterization of sleep disorders in Greek mythology. The search found several observations in clinical sleep medicine concealed in ancient myths. Beyond the etymology of terms and reflective imaginations, these myths and their characters influence concepts that still tantalize our medical practice in modern days.

Melanotic Neuroectodermal Tumor of Infancy: the Use of Immunohistochemical Analysis.

The Melanotic Neuroectodermal Tumor of Infancy (MNTI) is an asymptomatic, pigmented neoplasm characterized by a fast and locally aggressive growth along with a rare tissue formation. In the diagnostic process, the use of imaging exams can suggest a local destruction suggestive of malignancy, a sign of bone remodeling and expansion. Therefore, as any early diagnosis minimizes risks and improves the prognosis of treatment for the patient, the aim of this study was, based on a clinical case report, to corroborate the use of histopathological analysis associated with immunohistochemistry. Thus, we conclude that the immunohistochemical exam is of great importance for a better complementation of the MNTI diagnosis process. In addition, it can reveal signs of possible aggressive growth.

Videogravação e videofeedback no ensino-aprendizagem de habilidades de exame físico / Video recording and videofeedback in teaching-learning of physical examination skills

Resumo: Introdução: O ensino de habilidades de exame físico, parte integrante e obrigatória dos currículos de escolas médicas, ocorre, tradicionalmente, com uma abordagem baseada na "demonstração e prática", e, embora existam outros modelos, não há, até o momento, nenhuma evidência de que um seja superior ao outro. Inovações nessa área são apontadas como caminho para suprir as deficiências de ensino-aprendizagem. Objetivo: Este estudo teve como objetivos descrever a incorporação da videogravação e do videofeedback no ensino-aprendizagem de habilidades de exame físico e avaliar a eficácia desses recursos. Método: Foi realizado um estudo historicamente controlado antes e depois da intervenção com alunos do primeiro ano de um curso de Medicina. O grupo de intervenção, em que se aplicaram a videogravação e o videofeedback, foi constituído de 91 alunos do semestre 2019.2, e o grupo controle contou com 72 alunos do semestre 2018.1. Ambas as turmas realizaram duas avaliações teóricas somativas (T1 e T2) e duas práticas, no formato de um exame clínico objetivo estruturado (OSCE). Na análise estatística comparativa das notas de ambas as turmas, utilizaram-se os testes não paramétricos da soma de postos de Wilcoxon-Mann-Whitney. Resultado: A mediana das notas das avaliações práticas (primeiro e segundo OSCEs) de 2019 foram maiores do que as de 2018. Constatou-se ainda que a turma de 2019 teve uma evolução positiva das suas notas práticas passando de uma mediana de 11,6 no primeiro OSCE para 13,85 no segundo OSCE, o que também ocorreu com as provas teóricas (p < 0,05). Já na turma de 2018, houve queda da mediana das notas da T1 para T2 e do primeiro OSCE para o segundo OSCE, mas sem significância estatística. Conclusão: A incorporação da videogravação e videofeedback no ensino-aprendizagem de habilidades de exame físico entre graduandos do primeiro ano do curso de Medicina, em ambientes simulados, mostrou-se efetiva na melhora do desempenho dos discentes em avaliações teóricas e práticas. Essa abordagem se mostra ainda como meio de desenvolvimento e aplicação de uma aprendizagem motora observacional, reflexiva, experiencial e da metacognição no ensino-aprendizagem de habilidades de exame físico entre estudantes de Medicina.

Abstract: Introduction: Physical examination skills, an integral and mandatory part of medical school curricula, are traditionally taught through an approach based on "demonstration and practice", and although other models exist, there is, to date, no evidence that one is superior to the other. Innovations in this area are pointed out as a way to supply deficiencies in teaching and learning. Objectives: To describe the incorporation of video recording and video feedback in the teaching-learning of physical examination skills and to evaluate the effectiveness of such approach. Method: A historically controlled study was carried out before and after the intervention with students in the first year of a medical course. The intervention group, in which video recording and video feedback was applied, consisted of 91 students from semester 2019.2 and the control group had 72 students from semester 2018.1. Both classes underwent two summative theoretical (T1 and T2) and two practical assessments, in the format of an objective structured clinical examination (OSCE). In the comparative statistical analysis of the grades of both classes, the non-parametric Wilcoxon and Mann Whitney rank test was used. Results: The median of the marks of the practical evaluations (1st and 2nd OSCE) of the 2019 class were higher than those of 2018. It was also found that the class of 2019 showed a positive evolution in its practical marks, with the median score increasing from 11.6 in the 1st OSCE to 13.85 in the 2nd OSCE, which also happened with the theoretical tests (p <0.05). In the class of 2018, there was a drop in the median mark from T1 to T2 and from the 1st OSCE to the 2nd OSCE, but without statistical significance. Conclusion: The incorporation of video recording and video feedback in teaching-learning physical examination skills among first-year medical students, in simulated environments, proved to be effective in improving student performance in both theoretical and practical assessments. This approach is also shown as a means of developing and applying observational, reflective, experiential and metacognition motor learning in the teaching-learning of physical examination skills among medical students.

Different etiologies of superficial siderosis / Diferentes etiologias de siderose superficial

Superficial Siderosis (SS) is an uncommon condition caused by hemosiderin deposition into the subarachnoid space. SS is characterized by cerebellar ataxia, progressive sensorineural hearing loss and pyramidal signs, but is often an unrecognized disorder. Magnetic Resonance Imaging (MRI) is the diagnostic procedure of choice due its high sensitivity to hemosiderin deposits in addition to being a non-invasive exam. This paper aims to describe a case of SS and to perform a literature review about SS etiologies, neuroimaging features and clinical characteristics. A 65-year-old man came to a neurology outpatient clinic with seizures and cerebellar ataxia with a history of car accident and severe traumatic brain injury 45 years ago. MRI SWAN showed a hyposignal in the cisterns of the base and on the cerebellar surface and T1-weighted images left hippocampal sclerosis.

A Siderose Superficial (SS) é uma condição rara causada por depósitos de hemossiderina no espaço subaracnóideo. SS é caracterizada por ataxia cerebelar, perda neurosensorial auditiva progressiva e sinais piramidais, mas é frequentemente uma desordem de difícil diagnóstico. A Ressonância Magnética (RM) é o exame de escolha para o diagnóstico devido a sua alta sensibilidade aos depósitos de hemossiderina, além de ser um exame não invasivo. Este artigo tem como objetivo descrever um caso de SS e realizar uma revisão da literatura sobre as etiologias da SS, suas características na neuroimagem e suas características clínicas. Um homem de 65 anos de idade procurou o ambulatório de neurologia com convulsões e ataxia cerebelar. Ele informou histórico de acidente automobilístico e lesão cerebral traumática grave há 45 anos. A RNM SWAN mostrou hipossinal nas cisternas da base e na superfície cerebelar e as imagens em T1 evidenciaram a presença de esclerose hipocampal esquerda.

Photodynamic Therapy With Propolis: Antibacterial Effects on Staphylococcus aureus, Streptococcus mutans and Escherichia coli Analysed by Atomic Force Microscopy.

Introduction: Photodynamic therapy (PDT) is a process that uses a light source (e.g. laser), oxygen molecules and a photosensitizing agent. PDT aims to act against pathogens, including those resistant to antimicrobials. The association of PDT with natural drugs, such as Propolis, has not been widely studied. Methods: Therefore, this study aimed to evaluate the antimicrobial effect of PDT in vitro by using Propolis as a photosensitizing agent. For this purpose, the dry Propolis extract was used as a photosensitizer and a low-power laser (Photon Laser III model) was irradiated onto the microwells for 90 seconds. Gram-positive and Gram-negative bacterial strains were used in the tests at a concentration of 5 × 105 CFU/mL. Initially, the antibacterial activity of the photosensitizers without laser action was determined by using a serial microdilution method before the experiment with a laser. After the incubation of the plates in a bacteriological oven, resazurin (0.1%) was added and the minimum inhibitory concentration (MIC) was determined. Alterations in the morphology of the bacteria were analysed by using atomic force microscopy (AFM). Results: Bacteria were sensitive to Propolis with MICs ranging from 13.75 to 0.85 mg/mL, but no susceptibility was observed for methylene blue without laser application. A change was observed for MIC values of Propolis against Staphylococcus aureus after irradiation, which decreased from 1.71 mg/mL to 0.85 mg/mL. However, this behaviour was not observed in Escherichia coli, the only gram-negative strain used. In addition, AFM images revealed alterations in the size of one of the bacteria tested. Conclusion: The Propolis is more active against gram-positive bacteria and PDT improved its activity against one of the strains tested.

Medication-Related Osteonecrosis of the Jaw and Low-Level Laser Therapy as Adjuvant Treatment: A Case Report.

Introduction: Medication-related osteonecrosis of the jaw (MRONJ) occurs by the use of a drug that has osteonecrosis as one of its side effects. Case Report: We describe a case of a 48-year-old oncological patient who had brain and bone metastasis due to breast cancer and was medicated with bisphosphonates (BPs). She presented cavities, and after an incorrect exodontia, the lesion evolved into a jaw osteonecrosis. Then she did a sequestrectomy and was treated using laser therapy. Radiological and clinical features are also described. Conclusion: In a case like this, we notice how necessary is a complete evaluation of the oncological patient before some procedures and laser therapy as an effective ally in the management.

Complex fibroadenoma: bibliometric literature review and presentation of a clinical case

Fibroadenomas (FAs) are benign fibro-epithelial tumours of the breast characterized by being biphasic and having stromal and epithelial components. It is estimated that FAs affect more than 20 percent of the general population aged 16­40 years old. Complex FAs are a sub-type of fibroadenoma presenting one or more pathological characteristics, such as epithelial calcifications, apocrine metaplasias, sclerosing adenoma and cysts larger than 3 mm. According to studies elsewhere, women with complex FAs are 3.1 times more likely to develop breast cancer. The objective of the present study was to map the scientific production of articles on complex FA in the international literature. The ISI Web of Knowledge (Web of Science), one of the main scientific databases in the world, was searched with the following terms: ("complex" and "fibroadenoma") or ("fibroadenoma" and "complex"). Only articles published between 1981 and 2019 were considered for a bibliometric review, in which 160 articles from 126 different periodicals were identified after using refinement filters. Moreover, a clinical case was also discussed based on the patient's medical record and interview

Diagnostic value of magnetic resonance imaging in the analysis of ameloblastoma: report of two cases / Valor diagnóstico da ressonância magnética na análise do ameloblastoma: relato de dois casos

Ameloblastoma is an odontogenic tumor that shares clinical and imaging characteristics with other lesions of the jaws, such as odontogenic keratocyst, which makes the diagnosis difficult.However, in addition to radiographic and tomographic examinations, Magnetic Resonance Imaging (MRI) has been increasingly used, contributing with relevant additional information about thedifferentiation between solid and liquid components of the lesion. This case report was conducted to present two variations of ameloblastoma and discuss the radiographic, tomographic and MRI contribution in the differential diagnosis between ameloblastoma and odontogenic keratocyst. The signal intensity in T1-weighted MRI revealed internal fluid content in both cases, which was important in the differential diagnosis with other intraosseous lesions such as odontogenic keratocysts. This is probably due to the presence of keratin that increases the viscosity of the content and also for an intermediate signal intensity signal in T2-weighted MRI. Therefore, MRI revealed important internal characteristics of the reported lesions, which was very useful in the establishment of the differential diagnosis with other lesions. (AU)

O ameloblastoma é um tumor odontogênico que compartilha características clínicas e de imagem com outras lesões da mandíbula, como o ceratocisto odontogênico, o que dificulta o seu diagnóstico. Entretanto, além dos exames radiográficos e tomográficos, a ressonância magnética (RM) tem sido cada vez mais utilizada, contribuindo com informações adicionais relevantes sobre a diferenciação entre componentes sólidos e líquidos da lesão. Este relato de caso apresenta duas variações de ameloblastoma e discuti a contribuição radiográfica, tomográfica e da RM no diagnóstico diferencial entre o ameloblastoma e o ceratocisto odontogênico. A RM ponderada em T1 revelou conteúdo líquido interno em ambos os casos relatados, o que foi importante no diagnóstico diferencial com outras lesões intraósseas, como os ceratocistos odontogênicos. Isto ocorre devido à presença de queratina aumentar a viscosidade do conteúdo e também gerar um sinal de intensidade intermediária na RM ponderada em T2. Portanto, a RM revelou importantes características internas das lesões relatadas, o que foi muito útil no estabelecimento do diagnóstico diferencial com outras lesões. (AU)

3D Reconstruction and Prediction of Sialolith Surgery.

Imaging examinations play an important role in the diagnosis of sialolithiasis, whose symptoms are initially confounded with other diseases. The objective of the present case report is to highlight imaging and processing techniques as well as image analysis for the preoperative assessment and planning of surgical interventions and adequate treatment of massive sialoliths. A 35-year-old male patient presented complaining of pain in the submandibular region and purulent secretions from a lingual caruncle with slightly increased volume in the region. Imaging examinations were ordered as follows: cone beam computed tomography, ultrasonography, and three-dimensional reconstruction, including clinical evaluation. A final diagnosis of sialolithiasis was established. Surgery was indicated and carried out by using a lateral transcervical approach for complete resection of the gland, which was based on the calculation of the total volume of the sialolith, thus increasing the surgery's success.

Evaluation measure of 3d volumetry of masseter hypertrophy: association with modalities of imaging / Avaliação de medidas volumétricas 3D da hipertrofia massetérica em dois casos: associação com modalidades de imagem

Abstract Masseteric hypertrophy is a benign condition, asymptomatic and rare, characterized by the excessive development of the masseter muscle, which usually results in aesthetic complaints. The imaging exams for differential diagnosis of pathologies in the parotid-masseteric region is always recommended. This work aims the imaging characterization of masseteric hypertrophy through the report of two clinical cases combining different imaging modalities: panoramic radiography, magnetic resonance imaging, computed tomography, ultrasonography and 3D volumetry. Two male subjects with no family history of masseteric hypertrophy were referred to a diagnostic center in dentomaxillofacial radiology due to an increase in bilateral facial volume in the masseteric region. Images of the panoramic radiography showed an increase of the bilateral mandibular angle in both cases. Using computerized tomography, bilateral masseter muscle hypertrophy was demonstrated in the patients, and magnetic resonance scan and ultrasound examination were performed for better visualization and muscle measurement. 3D volumetry assessment of musculature showed as additional tool to evaluate the status of the masseter muscles in patients with Masseteric hypertrophy. Therefore, the association of imaging examinations allowed to perform the imaging characterization of masseteric hypertrophy with presence of bone exostosis.

RESUMO A hipertrofia massetérica é uma condição benigna, assintomática e rara, caracterizada pelo desenvolvimento excessivo do músculo masseter, que geralmente resulta em queixas estéticas. São sempre recomendados os exames de imagem para diagnóstico diferencial de patologias na região parotídea-massetérica. Neste trabalho objetiva-se a caracterização da imagem da hipertrofia massetérica através do relato de dois casos clínicos combinando diferentes modalidades de imagem: radiografia panorâmica, ressonância magnética, tomografia computadorizada, ultra-sonografia e volumetria 3D. Dois indivíduos do sexo masculino sem história familiar de hipertrofia massetérica foram encaminhados para um centro de diagnóstico em radiologia dentomaxilofacial devido ao aumento do volume facial bilateral na região massetérica. As imagens da radiografia panorâmica mostraram um aumento do ângulo mandibular bilateral em ambos os casos. Usando tomografia computadorizada, foi demonstrada hipertrofia muscular massetérica bilateral nos pacientes, e a varredura de ressonância magnética e ultra-sonografia foram realizadas para melhor visualização e medição. A avaliação volumétrica em 3D da musculatura mostrou-se como ferramenta adicional para avaliar o estado dos músculos masseteros em pacientes com hipertrofia massetérica. Portanto, a associação de exames de imagem permitiu realizar a caracterização da imagem da hipertrofia massetérica com presença de exostose óssea.

Corrigendum to "Biological Effects of Medicinal Plants on Induced Periodontitis: A Systematic Review".

[This corrects the article DOI: 10.1155/2016/3719879.].

Assessment of the opening diameter of the incisive foramen as a parameter for gender and age estimation / Avaliação do diâmetro de abertura do forame incisivo como parâmetro de estimativa de sexo e idade

Objective: To analyse the opening diameter of incisive foramen as a parameter for gender and age estimation by using cone beam computed tomography (CBCT). Material and Methods: After approval by the local research ethics committee, CBCT images were obtained from the dental database of a diagnostic centre and then selected. Images suggesting presence of periapical lesions and periodontal changes were excluded, as well as those of patients undergoing orthodontic treatment, with trauma to the mid-facial third, with cleft/lip palate, cranial or syndromic morphological changes, or even absence of one of the upper incisors. The images of male and female patients were distributed according to age groups (i.e. 10-30 years, 31-50 years, and 51 years or older) and then assessed twice and independently by three surgeon-dentists with experience in radiology by means of the XoranCat® software. The resulting data were tabulated and statistically analysed by using the SAS® software (version 2003) ­ PROC GLM for mixed generalised models ­ and Tukey's test for comparison of the mean values at 5% significance level. Results: Considering the methodology used, the results have demonstrated no statistically significant difference in the method for gender estimation. However, it was observed that there was a gradual increase in the mean values as the age advances in the majority of the age groups for both males and females, with a statistically significant difference (P<0.05) regarding age estimation. Conclusion: The use of incisive foramen as a gender parameter has had a limited forensic value, but it is an innovative approach in the process of age estimation. (AU)

Objetivo: Analisar o diâmetro de abertura do forame incisivo como parâmetro de estimativa de sexo e idade utilizando exames de Tomografia Computadorizada de Feixe Cônico (TCFC). Material e Métodos: Mediante aprovação do Comitê de Ética em Pesquisa, selecionaram se exames de TCFC originários do arquivo odontológico de um determinado centro diagnóstico. Foram excluídos os exames que sugerissem presença de lesões periapicais, alterações periodontais, bem como de pacientes sob tratamento ortodôntico, com trauma no terço médio facial, com fissuras palatinas, alterações morfológicas em crânio ou sindrômicos, ou ainda ausência de qualquer um dos dentes incisivos superiores. As imagens foram distribuídas segundo faixa etária de 10 a 30 anos, 31 a 50 anos, 51 anos ou mais, de ambos os sexos, e avaliadas duas vezes por três Cirurgiões-Dentistas radiologistas de forma independente utilizando o software XoranCat®. Os dados foram tabulados e analisados estatisticamente através do Software SAS®, versão 2003, por meio do PROC GLM, modelos mistos generalizados e o teste de comparação de médias foi o Tukey a 5% de significância. Resultados: Considerando a metodologia adotada, os resultados não demonstraram diferença estatisticamente significante que pudesse sugerir um método de estimativa de sexo. Porém, percebeu-se que houve um aumento gradativo das médias encontradas conforme o avanço da idade para ambos os sexos na maioria dos grupos, além de uma diferença estatisticamente significante (p<0,05) em relação à estimativa de idade. Conclusão: A utilização do forame incisivo como parâmetro dimórfico entre sexos demonstrou limitado valor forense, mas apresenta uma proposta inovadora no processo de estimativa de idade. (AU)

Prosthetic Management of a Child with Hypohidrotic Ectodermal Dysplasia: 6-Year Follow-Up.

Ectodermal dysplasia (ED) is a genetically heterogeneous condition resulting from clinical anomalies of structures derived from the ectoderm, such as the hair, nails, sweat glands, and teeth. This clinical report presents the case of a child diagnosed with hypohidrotic ED at 2 years of age; clinical and imaging evaluation was performed with 6-year follow-up, and we present details of the prosthetic dental care, with a 12-month follow-up. The patient's masticatory capacity had improved, leading to the child gaining 4 kg. In conclusion, prosthetic management was noninvasive and appeared to lead to developmental benefits for the patient.

Value of Magnetic Resonance Imaging for Diagnosis of Dentigerous Cyst.

Odontogenic cysts have a high prevalence in the dental clinic population, with dentigerous cyst being one of the most frequent ones and whose aetiology involves accumulation of fluid between the reduced enamel epithelium and the crown of an unerupted tooth. In the diagnostic process of these lesions, one should consider complementary imaging exams such as conventional radiography and computed tomography, which are commonly used for providing anatomical information on the tissues compromised by the lesion, but not on the nature of it. Magnetic resonance imaging (MRI) scans are noninvasive modalities which, due to their unique acquisition characteristics, can provide distinct information on the nature of the lesion. This study reports on a case of dentigerous cyst in the mandible of a 9-year-old patient, documented by means of different imaging modalities. MRI played an important role in both diagnosis of the lesion and differential diagnosis between neoplastic lesions presenting similar imagenological behaviour under other techniques of radiography.

Biological Effects of Medicinal Plants on Induced Periodontitis: A Systematic Review.

Objective. The aim of this systematic review was to investigate the advances in the study of medicinal plants and their biologic effects on periodontitis in animal models. Study Design. A systematic search was conducted by three independent researchers, who screened articles published up to March/2016, to identify the studies that contained sufficient and clear information on the association of the medicinal plants and periodontitis in murine models. The searches were performed using PubMed, Cochrane, and Science Direct databases. Results. After a critical analysis of titles and abstracts, 30 studies were finally eligible for analysis. The studies presented a great diversity of the experiment designed regarding the methods of induced periodontitis and the evaluation of the medicinal plants efficacy. None of the studies described the possible toxic effects associated with the administration of the plant material to animals and whether they could prevent damage to organs caused by systemic effect of induced periodontitis. Gel-based formulations containing plant substances are seen as an interesting strategy to treat periodontitis. Conclusions. In this systematic review, the state-of-the-art knowledge on the medicinal plants and the induced periodontitis was critically evaluated and discussed from the experiment designed to the possible clinical application.

Imaging Aspects of Palatal Torus in Cone Beam Computed Tomography and Magnetic Resonance: Case Report.

The torus palatinus is a unilocular or multilocular exostosis that occurs in the midline of the hard palate. It is considered a common clinical finding. Magnetic resonance imaging (MRI) is not commonly used in dentistry and descriptions of the torus by this imaging method are therefore rare in the literature. This case study reports on a female patient referred to the dentist to elucidate a bone enlargement detected by MRI, which was requested by the physician who accompanied the patient for migraine treatment. Additional routine dental imaging exams were performed for the planning of different treatments. Here is a description of the torus palatinus along with MRI in order to provide a complete representation of the clinical finding.

Solitary fibrous tumos ot the hard palate: a rare entity in oral Cavity / Tumor fibroso solitário do palato duro: um achado raro na cavidade bucal

Um caso de tumor fibroso solitário em cavidade oral é reportado. O tumor fibroso solitário é uma neoplasia rara caracterizada por uma proliferação de células fusiformes de origem mesenquimatosa e é responsável por menos de 2% de todos os tumores de tecidos moles. No presente caso, o diagnóstico clínico inicial foi direcionado para um tumor de glândula salivar em decorrência da localização em palato duro. Histologicamente, o tumor era composto por tecido conjuntivo com proliferação de células fusiformes e ovaladas. Imunoistoquímica da lesão foi positiva para CD34 e CD99. A lesão foi tratada por ressecção cirúrgica. Os dados clínicos, imaginológicos, histológicos eimunoistoquímica são discutidos neste estudo.

A case of solitary fibrous tumor is reported. Solitary fibrous tumor is a rare neoplasia characterized by the proliferation offusiform cells of mesenchymal origin accounting for at least 2% of all soft tissue tumors.In this present case, the initial diagnosis was salivary gland tumor because of the location in the hard palate. Histologically, the tumor was composed by conjunctive tissue with proliferation of oval and fusiform cells. The immunohistochemical analysis was positive for CD34 and CD99. The lesion was treated by surgical resection. The clinical, imaging, histological and immunohistochemical data are discussed in this study

Epidemiological survey of oral and maxillofacial complex biopsies: 13 year retrospective study / Levantamento epidemiológico de biópsias do complexo bucomaxilofacial: um estudo retrospectivo de 13 anos

To conduct a retrospective study through epidemiological survey of the biopsies oforal cavity performed at the Center of Pathology, Cytology, and Cytopathology– CEPACC in Parnaíba-PI, from 1998 to 2011. Material and Methods: One hundred and thirty-nine referrals and reports were analyzed by evaluating the group and prevalence of oral lesions, anatomic allocation, and distribution in relation to type, gender, and age. Results: Females (52%) showed the greatest prevalence, observing more cases in the age range of 41 to 60 years. The lip was the preferable location of the analyzed lesions. The groups of the lesions in salivary glands (17%), malignant tumors of epithelial origin, benign tumors of conjunctive origin, premalignant lesions of epithelial origin, and odontogenic cystswere the most common lesions. Considering the isolated lesions, squamous cell carcinoma was themost frequent. We observed a greater preference for salivary gland lesions, although great diversityof clinical cases was found. Conclusion: Thereported lesions occurred mostly in adult females and in groups with salivary gland diseases...

O presente trabalho teve como objetivo realizar um estudo retrospectivo através de um levantamento epidemiológico das biópsias da cavidade oral realizadas no Centro de Patologia, Citologia e Citopatologia –CEPACC em Parnaíba-PI, no período de 1998 a 2011. Material e Métodos: Foram analisadas 139 requisições e laudos dos arquivos, avaliando-se o grupo e prevalência das lesões orais, a localização anatômica e a distribuição das mesmas quanto ao tipo, sexo e idade. Resultados: Houve um predomínio do gênero feminino (52%), observando-se maior número de casos na faixa etária de 41 a 60 anos, com o lábio como local preferencial das lesões analisadas. Os grupos das lesões de glândulas salivares (17%), tumores malignos de origem epitelial,tumores benignos de origem conjuntiva, lesões pré malignas de origem epitelial e cistos odontogênicos foram os mais comuns. Considerando-se as lesões de forma isolada, o carcinoma epidermóide foi o mais frequente. Observou-se ainda predileção maior para as lesões de glândulas salivares, embora houvesse grande diversidade para o número encontrado de casos clínicos. Conclusão: Concluiu-se que as lesões relatadas foram com maior frequência em mulheres adultas e em grupos como doenças de glândulas salivares...